7.alpha.-Halogeno-3,20-dioxo-1,4-pregnadienes, methods for their

Details 7.alpha.-Halogeno-3,20-dioxo-1,4-pregnadienes, methods for their 7.alpha.-Halogeno-3,20-dioxo-1,4-pregnadienes, methods for their

1977-11-07

1978-11-07

Roberts, Elbert L.

Drug, bio-affecting and body treating compositions

Antigen, epitope, or other immunospecific immunoeffector

Bacterium or component thereof or substance produced by said...

26023955D, 2603971, 2603974, 26039745, 26039747, 424243, C07J 500, A61K 3158

Patent

active

041247078

ABSTRACT:
Novel 3,20-dioxo-7.alpha.-halogeno-1,4-pregnadienes are described and their use as anti-inflammatory agents. Preferred are 7.alpha.-bromo- and 7.alpha.-chloro- derivatives, particularly 7.alpha.-bromo- and 7.alpha.-chloro-1,4-pregnadienes-11.beta.,17.alpha.,21-triol-3,20-dione 17,21-dihydrocarboncarboxylates, the 16-methyl and 16-methylene derivatives thereof being particularly valuable as topical anti-inflammatory agents.

REFERENCES:
patent: 2819264 (1958-01-01), Gould et al.

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