7-[.alpha.-(Benzimidazol-2-ylcarbonylamino)-arylacetamido]ephalo

Details 7-[.alpha.-(Benzimidazol-2-ylcarbonylamino)-arylacetamido]ephalo 7-[.alpha.-(Benzimidazol-2-ylcarbonylamino)-arylacetamido]ephalo

1976-05-20

1977-09-13

Rizzo, Nicholas S.

Organic compounds -- part of the class 532-570 series

Organic compounds

Chalcogen in the nitrogen containing substituent

424246, 544 28, C07D50120

Patent

active

040481611

ABSTRACT:
Cephalosporin antibiotics of the formula ##STR1## in which, for example, R is phenyl, hydroxyphenyl, halophenyl, thienyl, or furyl; R.sub.1 is hydrogen, carbamoyloxy, acetoxy, a lower alkyl substituted 1H-tetrazol-5-ylthio or 1,3,4-thiadiazol-5-ylthio group; and R.sub.2 is hydrogen, C.sub.1 -C.sub.3 alkyl, C.sub.1 -C.sub.3 alkoxy, chloro, bromo, or fluoro; are highly active broad spectrum antibiotics especially useful in the treatment of infections attributable to the gram-negative microorganisms.

REFERENCES:
patent: 3867380 (1975-02-01), Dunn et al.

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