7-[.alpha.-(2,3-DIHYDRO-2-OXO-1H-benzimidazol-1-ylcarbonyl-amino

Details 7-[.alpha.-(2,3-DIHYDRO-2-OXO-1H-benzimidazol-1-ylcarbonyl-amino 7-[.alpha.-(2,3-DIHYDRO-2-OXO-1H-benzimidazol-1-ylcarbonyl-amino

1976-06-21

1977-12-06

Rizzo, Nicholas S.

Organic compounds -- part of the class 532-570 series

Organic compounds

Heterocyclic carbon compounds containing a hetero ring...

424246, 544 26, 544 27, C07D50134

Patent

active

040618617

ABSTRACT:
Cephalosporin antibiotics of the formula ##STR1## in which, for example, R is phenyl, hydroxyphenyl, halophenyl, thienyl, or furyl; R.sub.1 is hydrogen, carbamoyloxy, acetoxy, a lower alkyl substituted 1H-tetrazol-5-ylthio or 1,3,4-thiadiazol-5-ylthio group; and R.sub.2 is hydrogen or methyl; are highly active broad spectrum antibiotics especially useful in the treatment of infections attributable to the gram-negative microorganisms.

REFERENCES:
patent: 3966709 (1976-06-01), Konig et al.
70-02178, 1/24/70, Japan Fuji. Ltd., 260/243c 6 pp. (Abstract 121564g C.A., vol. 72, 1970).

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