7-Acylamino-desacetoxy-cephalosporanic acid esters and their pro

Details 7-Acylamino-desacetoxy-cephalosporanic acid esters and their pro 7-Acylamino-desacetoxy-cephalosporanic acid esters and their pro

1974-03-26

1976-02-03

Rizzo, Nicholas S.

Chemistry of carbon compounds

Miscellaneous organic carbon compounds

C-metal

260622P, C07D50118, C07D50110

Patent

active

039364470

ABSTRACT:
7-Acylamino-desacetoxy-cephalosporanic acid esters are produced by heating a sulfoxide of 6-acylaminopenicillanic acid ester at a temperature of from about 60.degree.C to about 150.degree.C in the presence of a phenol catalyst. The 7-acylamino-desacetoxy-cephalosporanic acid esters produced are known per se and are useful as intermediates for the preparation of desacetoxy-cephalosporin derivatives which exhibit antibacterial activity.

REFERENCES:
toshiyasu et al., Chem Abs., 78, 111301d, (1973).

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