7,8-Dihydroxy-1-(sulfamylphenyl)-2,3,4,5-tetrahydro-1H-3-benzaze

Details 7,8-Dihydroxy-1-(sulfamylphenyl)-2,3,4,5-tetrahydro-1H-3-benzaze 7,8-Dihydroxy-1-(sulfamylphenyl)-2,3,4,5-tetrahydro-1H-3-benzaze

1979-10-11

1981-08-25

Love, Ethel G.

Drug, bio-affecting and body treating compositions

Antigen, epitope, or other immunospecific immunoeffector

Bacterium or component thereof or substance produced by said...

260239BB, 2603403, 2603405R, 424278, 424282, A61K 3133, A61K 3136, A61K 31335, C07D22316

Patent

active

042859387

ABSTRACT:
New 7,8-dihydroxy-1-(sulfamylphenyl)-2,3,4,5-tetrahydro-1H-3-benzazepines having pharmaceutical activity together with new intermediates and methods of synthesis for preparing them. The lead compound is 6-chloro-7,8-dihydroxy-1-(p-sulfamylphenyl)-2,3,4,5-tetrahydro-1H-3-benzaz epine which has very potent renal dopaminergic activity.

REFERENCES:
patent: 3496166 (1970-02-01), Mall et al.
patent: 3906006 (1975-09-01), Brossi et al.
patent: 4104379 (1978-08-01), Gallagher, Jr. et al.
patent: 4160765 (1979-07-01), Weinstock
patent: 4160766 (1979-07-01), Bream
patent: 4171359 (1979-10-01), Weinstock

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