7,8-difluoro-2,3-dihydro-3-methyl-4H-1,4-benzoxazine

Details 7,8-difluoro-2,3-dihydro-3-methyl-4H-1,4-benzoxazine 7,8-difluoro-2,3-dihydro-3-methyl-4H-1,4-benzoxazine

1997-03-19

1999-11-16

Raymond, Richard L.

Organic compounds -- part of the class 532-570 series

Organic compounds

Amino nitrogen containing

C07C21568

Patent

active

059861401

ABSTRACT:
7,8-difluoro-2,3-dihydro-3-methyl-4H-1,4-benzoxazine.

REFERENCES:
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patent: 4958045 (1990-09-01), Grohe et al.
patent: 5136059 (1992-08-01), Fujiwara et al.
Emerson et al., The Reductive Alkylation of Aniline, Journal Amer. Chem. Soc. pp. 2023-2025, 1938.
Emerson et al., The Reductive Alkylation of Aromatic Primary Amines II Journal Amer. Chem. Soc. pp. 3145-3148, 1938.
Hayakawa et al., Synthesis and Antibacterial Activities of Substituted 7-Ox0-2,3-dihydro-7H-pyrido[1,2,3-de] [1,4]benzoxazine-6-carboxylic Acids: pp. 4907-4913--Chem. Pharm. Bull., 1984.
Tanaka et al., Synthetics of Antimicrobial Agents. VII. Synthesis and Antibacterial Activities of Furo [2,3-g]quinoline Derivatives: pp. 4923-4928, Chem. Pharm. Bull. 32, 1984.
Egawa et al., A New Synthesis of 7-H-Pyrido [1,2,3-de] [1,4] benzoxazine Derivatives Including an Antibacterial Agent, Ofloxacin, pp. 4098-4102: Chem. Pharm. Bull. 32, 1986.
Katrizky et al., N-Alkylation of Hindered Secondary Aromatic Amines With 2-Iodobutane: pp. 399-402, Organic Preparation and Procedures Int., 23 (4) 1991.
Radl et al., Structural Modification and New Methods For Preparation 'Of Ofloxacin Analogs: pp. 1937-1943, Collect. Czech. Chem. Commun. (vol. 56) 1991.

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