7,8,9,10-tetrahydro-6-oxo-6H-dibenzo(b,d)pyranyloxy-propanes

Organic compounds -- part of the class 532-570 series – Organic compounds – Heterocyclic carbon compounds containing a hetero ring...

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549 5, C07D31108

Patent

active

046819541

ABSTRACT:
Dibenzopyrone derivatives which possess depressant and/or antihypoxia activity are 7,8,9,10-tetrahydro-6-oxo-6H-dibenzo[b,d]pyranyloxy-propanes having the formula (1): ##STR1## where R represents hydrogen or (C.sub.1 -C.sub.4) alkyl; where A represents chlorine or hydroxyl; and where B represents hydrogen, (C.sub.1 -C.sub.4) alkyl, 7-coumarinyl, phosphono, phenyl, or phenyl substituted with amino, dimethylamino, hydroxyl methoxyl, carboxyl, carboxymethyl, or 2-carboxyethenyl. Also included are pharmaceutically acceptable salts of the compounds.
Compounds of this invention are useful as sedatives or for the protection of warm blooded animals from the effects of oxygen depreviation.

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Gesquiere J. C. et al., Ann. Pharmaceutiquies Francasises 40 (3), 251-257 (1982).

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