7-{3-Hydroxy-2-[4-hydroxy-4-(lower alkyl)-trans-1-octen-1-yl]-5-

Details 7-{3-Hydroxy-2-[4-hydroxy-4-(lower alkyl)-trans-1-octen-1-yl]-5- 7-{3-Hydroxy-2-[4-hydroxy-4-(lower alkyl)-trans-1-octen-1-yl]-5-

1975-12-22

1977-11-29

Gerstl, Robert

Organic compounds -- part of the class 532-570 series

Organic compounds

Carboxylic acid esters

2603457P, 2603458P, 2604488R, 260514D, 424305, 424317, 560231, 542426, C07C17700

Patent

active

040606910

ABSTRACT:
7-{3-Hydroxy-2-[4-hydroxy-4-(lower alkyl)-trans-1-octen-1-yl]-5-oxocyclopent-1-yl{heptanoic acids and esters, displaying valuable pharmacological properties, e.g., gastric anti-secretory, are produced by the reaction of a 7-(3-oxygenated-5-oxocyclopent-1-en-1-yl)heptanoic acid or ester with the appropriate organometallic reagent.

REFERENCES:
patent: 3950406 (1976-04-01), Floyd
patent: 3965143 (1976-06-01), Collins et al.
Collins et al., Tet. Letters, 4217, (1975).

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