7[(2-Thiazolyl)-2-(oxoimino)acetamido]cephalosporin derivatives

Details 7[(2-Thiazolyl)-2-(oxoimino)acetamido]cephalosporin derivatives 7[(2-Thiazolyl)-2-(oxoimino)acetamido]cephalosporin derivatives

1978-08-01

1980-04-29

Wheeler, David

Drug, bio-affecting and body treating compositions

Antigen, epitope, or other immunospecific immunoeffector

Bacterium or component thereof or substance produced by said...

544 22, 544 25, 544 27, 544 28, A61K 31545, C07D50134, C07D50136, C07D50146

Patent

active

042005752

ABSTRACT:
Novel [2-(syn)-carbamoyloximinoacetamido]cephalosporins of the formula: ##STR1## [wherein, Y.sup.1 is hydrogen, hydroxyl, carbamoyloxy, acyloxy, quaternary ammonium or nitrogen-containing heterocyclic thio; R.sup.1 is alkyl, aralkyl or aryl; R.sup.2 is hydrogen or an ester residue; k is 0 or 1] and a salt thereof show strong antibacterial activities particularly against Gram-negative bacteria and they are useful as antibacterial agents.

REFERENCES:
patent: 4024134 (1977-05-01), Gregson et al.
patent: 4024137 (1977-05-01), Cook et al.
patent: 4098888 (1978-07-01), Ochiai et al.

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