7-(2-(Substituted benzoyl)amino)acetamido)cephalosporins

Details 7-(2-(Substituted benzoyl)amino)acetamido)cephalosporins 7-(2-(Substituted benzoyl)amino)acetamido)cephalosporins

1976-08-26

1982-03-09

Coughlan, Jr., Paul M.

Organic compounds -- part of the class 532-570 series

Organic compounds

Chalcogen in the nitrogen containing substituent

544 16, 544 24, 544 25, 544 27, 544 28, 544 29, 544 30, 548259, C07D50152

Patent

active

043190286

ABSTRACT:
Cephalosporin antibiotics of the formula ##STR1## wherein R is cyclohexadienyl, phenyl or substituted phenyl, 2-thienyl, 3-thienyl, 2-furyl or 3-furyl; R.sub.1 is a substituted phenyl having 1 to 4 hydroxy substituents or 1 to 3 amino substituents; and wherein Q is halo, methoxy, methyl or a group of the formula --CH.sub.2 R.sub.2 wherein R.sub.2 is alkanoyloxy, carbamoyloxy, alkoxy, halo, pyridinium or substituted pyridinium or a group of the formula --SR.sub.3 wherein R.sub.3 is alkyl, phenyl, substituted phenyl or a 5 or 6 membered-heteroaryl group having from 1 to 4 heteroatoms selected from the group consisting of O, S, and N;
are highly active broad spectrum antibiotics especially useful in the treatment of infections attributable to the gram-negative microorganisms.

REFERENCES:
patent: 3352858 (1967-11-01), Crast et al.
patent: 3931170 (1976-01-01), Treuner et al.
Iwanami et al., Chemical Abstracts, 1976, vol. 85: 160,128(f).

Affiliated with

Also associated with

Rating

7-(2-(Substituted benzoyl)amino)acetamido)cephalosporins does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with 7-(2-(Substituted benzoyl)amino)acetamido)cephalosporins, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and 7-(2-(Substituted benzoyl)amino)acetamido)cephalosporins will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFUS-PAI-O-1841534