7[-2-Alkoxyamino(acetamido)]cephalosporin derivatives

Details 7[-2-Alkoxyamino(acetamido)]cephalosporin derivatives 7[-2-Alkoxyamino(acetamido)]cephalosporin derivatives

1978-02-24

1979-12-25

Wheeler, David

Organic compounds -- part of the class 532-570 series

Organic compounds

Chalcogen in the nitrogen containing substituent

544 19, 548251, 2603473, C07D50136

Patent

active

041806581

ABSTRACT:
Cephalosporins in a series having the formula ##STR1## wherein R.sup.1 is alkyl containing 1-4 carbon atoms or a nontoxic pharmaceutically acceptable salt thereof, were synthesized and found to be potent antibacterial agents especially when in the form of the syn isomers essentially free of the corresponding anti isomer.

REFERENCES:
patent: 4025626 (1977-05-01), Berges
patent: 4033950 (1977-07-01), Cook et al.
patent: 4079134 (1978-03-01), Berges
patent: 4098888 (1978-07-01), Ochiai et al.
patent: 4146710 (1979-03-01), Naito et al.

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