(6R)- and (6S)-diastereoisomers of an ammonium salts of N.sup.5

Details (6R)- and (6S)-diastereoisomers of an ammonium salts of N.sup.5 (6R)- and (6S)-diastereoisomers of an ammonium salts of N.sup.5

1992-11-13

1995-01-17

Daus, Donald G.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Heterocyclic carbon compounds containing a hetero ring...

544258, C07D47504

Patent

active

053825810

ABSTRACT:
There are described ammonium salts of N.sup.5 -methyl-5,6,7,8-tetrahydrofolic acid as well as processes for their preparation. These ammonium salts may be separated into the single (6R) and (6S)-diastereoisomers. The separated diastereoisomers may be transformed into the corresponding alkali metal or alkaline earth metal salts.

REFERENCES:
patent: 5124452 (1992-06-01), Gennari
patent: 5173488 (1992-12-01), Haeger
patent: 5223500 (1993-06-01), Gennari
Murakami, Chem. Abstr vol. 77 entry 66198s (1972).
Murakami Chem Abstr vol. 75 entry 64273x (1971).

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