60-amino-acid polypeptide

Details 60-amino-acid polypeptide 60-amino-acid polypeptide

1989-08-21

1993-04-13

Cashion, Jr., Merrell C.

Chemistry: natural resins or derivatives; peptides or proteins;

Peptides of 3 to 100 amino acid residues

25 or more amino acid residues in defined sequence

530300, 514 12, A61K 3700, A61K 3702, C07K 500, C07K 700

Patent

active

052024172

ABSTRACT:
Disclosed is a novel polypeptide whose N-terminus is EAQ and which is composed of 60 amino acids. The polypeptide is produced from human breast cancer cell MCF7, or human gastric cancer cell MKN-45 or KATO-III, which polypeptide has a isoelectric point of 4.3, a molecular weight of 6,661 and the following amino acid sequence: ##STR1##

REFERENCES:
Rio et al, Biological Abstracts, (1988), BA86:82222.
Mori et al, Biological Abstracts (1987), BA84:68106.
Naito et al., Biological Abstracts (1983), BA76:50786.
Luqmani et al, Biological Abstracts (1989) BA89:50020.
Mori et al., Biochemical and Biophysical Research Communications, vol. 155, No. 1, 366-372 (1988).

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