6'-thiomethylsubstituted spectinomycins

Details 6'-thiomethylsubstituted spectinomycins 6'-thiomethylsubstituted spectinomycins

1986-03-10

1988-03-08

Chan, Nicky

Organic compounds -- part of the class 532-570 series

Organic compounds

Heterocyclic carbon compounds containing a hetero ring...

549214, C07D32304, C07D49300

Patent

active

047300590

ABSTRACT:
Disclosed are 6'-thiomethylsubstituted spectinomycins (XII) which are useful in the same way as other spectinomycin pharmaceutical agents.
6'-Thiomethylsubstituted (XIV) and protected spectinomycin (XIII) intermediates useful in the production of 6'-thiomethylsubstituted spectinomycins (XII) and 6'-alkenylspectinomycins (IX) are also disclosed.

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J. Am. Chem. Soc., "Synthesis of (+)-Spectinomycin", Stephen Hanessian, 101, 5839-5841, (1979).

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