Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Heterocyclic carbon compounds containing a hetero ring...
Patent
1993-07-13
1995-03-07
Shah, Mukund J.
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Heterocyclic carbon compounds containing a hetero ring...
514259, 514260, 544284, 544285, 544287, 544289, 540544, A61K 31505, A01N 4354, C07D23996, C07D23972
Patent
active
053958381
ABSTRACT:
The invention relates to quinazoline derivatives, or pharmaceutically-acceptable salts thereof, which possess anti-tumour activity; to processes for their manufacture; and to pharmaceutical compositions containing them.
The invention provides a quinazoline of the formula: ##STR1## wherein R.sup.1 is hydrogen or amino, or alkyl or alkoxy each of up to 6 carbon atoms; or R.sup.1 is substituted alkyl or alkoxy each of up to 3 carbon atoms;
REFERENCES:
patent: 4447608 (1984-05-01), Jones et al.
patent: 4564616 (1986-01-01), Jones et al.
patent: 4857530 (1989-08-01), Berman et al.
patent: 4981856 (1991-01-01), Hughes
patent: 4992550 (1991-02-01), Hughes
Poster presentation made in Zurich in the week Sep. 3-9, 1989, G. M. F. Bisset et al.; "Synthesis of Lipophilic Analogues . . .".
Barker Andrew J.
Hughes Leslie R.
Marsham Peter R.
Oldfield John
Pegg Stephen J.
Grumbling Matthew V.
Imperial Chemical Industries plc
National Research Development Corporation
Shah Mukund J.
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