6-substituted mitomycin analogs

Details 6-substituted mitomycin analogs 6-substituted mitomycin analogs

1989-12-13

1992-03-24

Rizzo, Nicholas S.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Having -c-, wherein x is chalcogen, bonded directly to...

548422, C07D48714, A61K 3140

Patent

active

050989260

ABSTRACT:
Novel methods for treatment of neoplastic disease states in animals, which methods comprise administering a therapeutically effective amount of a compound of the formula IV, ##STR1## wherein: Y is hydrogen or lower alkyl; and X is a radical of the formula --O--R, wherein R is:

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