Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Heterocyclic carbon compounds containing a hetero ring...
Patent
1994-03-30
1995-11-28
Shah, Mukund J.
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Heterocyclic carbon compounds containing a hetero ring...
514323, 514411, 548436, 544142, 546200, A61K 31535, A61K 3141, C07D20990, C07D41302
Patent
active
054708532
ABSTRACT:
The present invention provides 4-amino-6-substituted-hexahydrobenz[cd]indoles which are useful in treating disease states which can be benefited by an alteration of 5-HT.sub.1.sbsb.A receptors.
REFERENCES:
patent: 2809974 (1957-10-01), Kornfeld, et al.
patent: 3336307 (1967-08-01), Shen
patent: 3671541 (1972-07-01), Bormann et al.
patent: 3674801 (1972-07-01), Bormann et al.
patent: 4057560 (1977-11-01), Bormann et al.
patent: 4110339 (1978-08-01), Bach et al.
patent: 4282240 (1981-08-01), Baldwin et al.
patent: 4576959 (1986-03-01), Flaugh
patent: 4745126 (1988-05-01), Leander
patent: 4853406 (1989-08-01), Rosentreter, et al.
patent: 4983622 (1991-01-01), Flaugh
patent: 5039820 (1991-08-01), Kress et al.
patent: 5292766 (1994-03-01), Clemens
patent: 5302612 (1994-04-01), Flaugh et al.
Martinelli et al., Tetrahedron Letters, 31(52), 7579-7582, 1990.
Vane, Tetrahedron Letters, 31(52), 7583-7586, 1990.
Flaugh, et al., J. Med. Chem., 1988, 31, 1746-1753.
Kornfeld, et al., J.A.C.S., 78, (1956).
Kruse, et al., J. Org. Chem., 49, 4761-4768 (1984).
Bach, et al., J. Med. Chem., 1980, 23, 481-491.
Glennon, J. Med. Chem., 30, 1 (1987).
T. W. Greene, Protective Group in Organic Synthesis, John Wiley and Sons (1981) Chapter 7.
J. W. Barton, Protective Group in Organic Synthesis, McOmie, ed., Plenum Press (1973) Chapter 2.
The Vocabulary of Organic Chemistry, Orchin, et al., John Wiley and Sons, Inc., publishers, p. 126. (1989).
Schoenberg, et al., J. Org. Chem., 39, p. 3327(1974).
Schoenberg, et al., J. Org. Chem., 39, p. 3318 (1974).
Tetrahedron Letters, 21, 4061 (1980), Raucher et al.
Nichols, et al., Org. Prep. & Proc. Int., 9, 277 (1977).
Leanna, et al., Tet. Lett., 30, 3935 (1989).
O. Mitsunobu, Synthesis, Jan. 1981, p. 1.
J. P. Freemer, et al., Synthesis, Dec. 1974, p. 894.
Sugi, et al., Bull Chem. Soc. Jap., 43, p. 1489 (1970).
Morrison & Boyd, Chapter 22, Organic Chemistry, 3rd Ed. (1973).
Wong, et al., J. Neural Transm., 71, 207-218 (1988).
Wong, et al., J. Neural Transm., 64, 251-269 (1985).
Flaugh Michael E.
Martinelli Michael J.
Boone David E.
Eli Lilly and Company
Grumbling Matthew V.
Shah Mukund J.
Taylor Douglas J.
LandOfFree
6-substituted-hexahydrobenz [CD] indoles does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with 6-substituted-hexahydrobenz [CD] indoles, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and 6-substituted-hexahydrobenz [CD] indoles will most certainly appreciate the feedback.
Profile ID: LFUS-PAI-O-2013821