6-Substituted-9-(2-hydroxyethyl)-1,2,3,4-tetrahydro carbazol-1-o

Details 6-Substituted-9-(2-hydroxyethyl)-1,2,3,4-tetrahydro carbazol-1-o 6-Substituted-9-(2-hydroxyethyl)-1,2,3,4-tetrahydro carbazol-1-o

1979-11-29

1981-06-02

Daus, Donald G.

Chemistry of carbon compounds

Miscellaneous organic carbon compounds

C-metal

424250, 544343, C07D20988, C07D24138

Patent

active

042710731

ABSTRACT:
The present invention relates to new, pharmacologically valuable 2,4,5,6-tetrahydro-1H-pyrazino-[3,2,1-jk]-carbazoles substituted in the 8-position having the formula I ##STR1## wherein R stands for an alkyl or alkoxy group having 1 to 4 carbon atoms or a fluorine, chlorine or bromine atom comprising reacting a 6,9-disubstituted 1,2,3,4-tetrahydrocarbazol-1-one of the formula II ##STR2## and X denotes a bromine, chlorine or iodine atom or the radical of the formula defined --O--SO.sub.2 --R' and R' is an alkyl radical having 1 to 3 carbon atoms, phenyl or tolyl, with ammonia.

REFERENCES:
patent: 3232945 (1966-02-01), Sigal
patent: 3352882 (1967-12-01), Caldo
patent: 3382249 (1968-05-01), Albertson
patent: 4057640 (1977-11-01), Biere
patent: 4179443 (1979-12-01), Berger

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