6-substituted-4-hydroxy-tetrahydropyran-2-ones

Details 6-substituted-4-hydroxy-tetrahydropyran-2-ones 6-substituted-4-hydroxy-tetrahydropyran-2-ones

1985-09-03

1989-06-20

Shaver, Paul F.

Organic compounds -- part of the class 532-570 series

Organic compounds

Heterocyclic carbon compounds containing a hetero ring...

549271, C07D31300, C07D31304

Patent

active

048410713

ABSTRACT:
6-Substituted-4-hydroxy-tetrahydropyran-2-ones, useful as anti-atherosclerotic agents, are obtainable by the process of the invention. The 6-substituents have a phenyl, naphthyl, tetrahydronaphthyl or indolyl nucleus bound through an ethenyl unit. The invention includes novel intermediates.

REFERENCES:
patent: 3418290 (1968-12-01), Bantjes et al.
patent: 4376733 (1983-03-01), Frimer
patent: 4610826 (1986-09-01), D'Angelo et al.

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