6-Substituted 2-naphthyl .alpha.-substituted acetamides

Details 6-Substituted 2-naphthyl .alpha.-substituted acetamides 6-Substituted 2-naphthyl .alpha.-substituted acetamides

1975-03-17

1976-08-31

Wyman, Daniel E.

Chemistry of carbon compounds

Miscellaneous organic carbon compounds

C-metal

2605005H, 260558S, 260559R, 424324, C07C10322

Patent

active

039781240

ABSTRACT:
2-Naphthyl acetic acid derivatives and the corresponding amides, esters, hydroxamic acids and addition salts thereof, optionally substituted at the .alpha.-position on the acetic acid moiety and/or at position 6 and/or at positions 1, 4, 7 or 8 on the naphthyl ring and optionally saturated at positions 3 and 4, are anti-inflammatory, analgesic, anti-pyretic and anti-pruritic agents. A pharmaceutical method of effecting treatment of inflammation, pain, pyrexia and pruritus by the administration of naphthyl acetic acid derivatives. A pharmaceutical composition for use in the treatment of the above maladies comprising a naphthyl acetic acid derivative.

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