6-substituted-1,2,3,4-tetrahydro-9H-carbazoles and

Details 6-substituted-1,2,3,4-tetrahydro-9H-carbazoles and 6-substituted-1,2,3,4-tetrahydro-9H-carbazoles and

1996-06-27

1998-01-13

Ramsuer, Robert W.

Organic compounds -- part of the class 532-570 series

Organic compounds

Heterocyclic carbon compounds containing a hetero ring...

514411, 5462767, 5483647, C07D20988

Patent

active

057081875

ABSTRACT:
This invention provides novel 6-substituted-1,2,3,4-tetrahydro-9H-carbazoles and 5-HT.sub.1F agonists which are useful for the treatment of migraine and associated disorders.

REFERENCES:
patent: 3642816 (1972-02-01), Mooradian
patent: 3959309 (1976-05-01), Mooradian
patent: 4775680 (1988-10-01), Gillard et al.
patent: 4827032 (1989-05-01), Boshagen et al.
patent: 4988820 (1991-01-01), Boshagen et al.
patent: 5039670 (1991-08-01), Boshagen et al.
patent: 5223517 (1993-06-01), Muller et al.
patent: 5464864 (1995-11-01), King et al.
Flaugh et al, Chemical Abstracts, vol. 126 No. 144,111 (1997).
J. Med. Chem., Frank D. King, et al., 36, 1993, pp. 1918-1919.
Prog. Neuro-Psychopharmacol. & Biol. Psychiat, Paul L. Wood, et al., "Ciclindole and Flucindole: Novel Tetrahydrocarbazolamine Neuroleptics", vol. 8, 1984, pp. 773-777.
Journal of Neurochemistry, Eitan Friedman, et al., "Effects of Conformationally Restrained Analogues of Serotonin on Its Updake and Binding in Rat Brain", 36(3), 1981, pp. 931-937.
Journal of Neurochemistry, E. Meller, et al., "Tetrahydro-.beta.-Carbolines: Specific Inhibitors of Type A Monoamine Oxidase in Rat Brain", vol. 28, 1977, pp. 995-1000.
Journal of Medicinal Chemistry, A. Mooradian, et al., "Communications to the Editor: Hydroxylated 2,3,4,9-Tetrahydro-1H-Carbazol-3-Amines. A New Class of Experimental Cardiotonic Drugs", 1975, vol. 18, No. 6, pp. 640-641.
Journal of Medicinal Chemistry, A. Mooradian, et al., "3-Aminotetrahydrocarbazoles as a New Series of Central Nervous System Agents", 1977, vol. 20, No. 4, pp. 487-492.
J. Chem. Soc. (C), Org., "Synthesis of 3-Amino-1,2,3,4-Tetrahydro-6-Hydroxycarbazole, Analogue of 5-Hydroxytryptamine", G. E. A. Coombes, et al., 1970, pp. 325-326.

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