6-Phenyl-4H-v-triazolo[1,5-a][1,4]benzodiazepines

Details 6-Phenyl-4H-v-triazolo[1,5-a][1,4]benzodiazepines 6-Phenyl-4H-v-triazolo[1,5-a][1,4]benzodiazepines

1973-12-20

1976-03-09

Rollins, Alton D.

Chemistry of carbon compounds

Miscellaneous organic carbon compounds

C-metal

2602475EP, 260268TR, 26029359, 260349, 260570AB, 424248, 424250, 424267, 424269, C07D48704

Patent

active

039431452

ABSTRACT:
Compounds of the class of 6-phenyl-4H-v-triazolo[1,5-a][1,4] benzodiazepines, which in the 3-position are unsubstituted or substituted, particularly by a carbamoyl group or a substituted carbamoyl group, their 5-oxides and their pharmaceutically acceptable acid addition salts have valuable pharmacological properties and are active ingredients for therapeutic compositions. In particular, these new compounds have an anticonvulsive and anti-aggressive action. Specific embodiments are N,N-dimethyl-6-phenyl-8-chloro-4H-v-triazolo [1,5-a][1,4]benzodiazepine-3-carboxamide and N,N-dimethyl-6-(o-fluorophenyl)-8-chloro-4H-v-triazolo [1,5-a][1,4]benzodiazepine-3-carboxamide.

REFERENCES:
patent: 3703525 (1972-11-01), Tawada et al.

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