6-phenyl-3-(piperazinyalalkyl)-2,4(1H,3H)-pyrimidinedione deriva

Details 6-phenyl-3-(piperazinyalalkyl)-2,4(1H,3H)-pyrimidinedione deriva 6-phenyl-3-(piperazinyalalkyl)-2,4(1H,3H)-pyrimidinedione deriva

1989-05-16

1990-08-21

Hollrah, Glennon H.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Having -c-, wherein x is chalcogen, bonded directly to...

514252, 540490, 544 91, 544278, 544295, 544309, 544363, 544395, A61K 31505, C07D40114

Patent

active

049506706

ABSTRACT:
A pyrimidinedione derivative which is a compound of formula (I): ##STR1## in which: R1 denotes hydrogen, a halogen, a methyl group or a methoxy group,

REFERENCES:
patent: 4625028 (1986-11-01), Smith
patent: 4845221 (1989-07-01), Stack et al.
J. Clark et al., "Heterocyclic studies. Part XIX. Some 6-(substituted phenyl)-uracil and -thiouracil derivatives", Journal of the Organic Chemical Society, vol. C. No. 10, 1971, pp. 1945-1948.
L. Strekowski et al., "Facile Preparation of 6-substituted uracils", Synthesis--Journal of Synthetic Organic Chemistry, No. 1, Jan. 1988, pp. 70-72.
M. M. Al-Arab, "Reactions off arylpropioalamides with arylacetamides", Chemical Abstracts, vol. 106, 1987, p. 650, No. 102199w.

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