6-(p-Acylaminophenyl)-4,5-dihydropyridaz-3-ones and therapeutic

Details 6-(p-Acylaminophenyl)-4,5-dihydropyridaz-3-ones and therapeutic 6-(p-Acylaminophenyl)-4,5-dihydropyridaz-3-ones and therapeutic

1981-01-14

1983-03-15

Berch, Mark L.

Drug, bio-affecting and body treating compositions

Antigen, epitope, or other immunospecific immunoeffector

Bacterium or component thereof or substance produced by said...

544239, C07D23704, A61K 3150

Patent

active

043767710

ABSTRACT:
6-(p-Acylaminophenyl)-4,5-dihydropyridaz-3-ones of the formula I ##STR1## where R.sup.1 is hydrogen or alkyl of 1 to 3 carbon atoms and R.sup.2, if R.sup.1 is hydrogen, is halogen-substituted alkyl of 3 to 6 carbon atoms or .beta.-haloethyl or, if R.sup.1 is alkyl of 1 to 3 carbon atoms, is halogen-substituted alkyl of 1 to 6 carbon atoms, their manufacture, and therapeutic agents which contain, as the active ingredient, a compound of the formula I, where R.sup.2 may also be halomethyl or .alpha.-haloethyl if R.sup.1 is hydrogen. These compounds may be used as anti-hypertensive agents and for the prophylaxis and therapy of thromboembolic disorders.

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patent: 3812256 (1974-05-01), Curran
patent: 3822260 (1974-07-01), Curran et al.
patent: 3824271 (1974-06-01), Allen, Jr.
patent: 3845050 (1974-10-01), Lebkuecher et al.
patent: 3975388 (1976-08-01), Hakim
patent: 4112095 (1978-09-01), Allen, Jr.

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