6-oxygenated corticoid 17.alpha.-carbonates and process for prod

Details 6-oxygenated corticoid 17.alpha.-carbonates and process for prod 6-oxygenated corticoid 17.alpha.-carbonates and process for prod

1984-08-28

1986-04-29

Roberts, Elbert L.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Cyclopentanohydrophenanthrene ring system doai

514179, 26039745, C07J 500

Patent

active

045857660

ABSTRACT:
Novel 6-oxygenated corticoid 17.alpha.-carbonates are disclosed. These compounds have strong topical anti-inflammatory activity which are accompanied by extremely weak systemic adverse reaction. The present compounds are useful for the treatment of acute and chronic eczema, eczema seborrhoicorum, contact dermatitis, atopic dermatitis, asthma, etc.

REFERENCES:
patent: 4242334 (1980-12-01), Stache et al.
patent: 4377575 (1983-03-01), Stache et al.

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