6-Oxamorphinans

Details 6-Oxamorphinans 6-Oxamorphinans

1979-05-14

1981-01-20

Daus, Donald G.

Organic compounds -- part of the class 532-570 series

Organic compounds

Heterocyclic carbon compounds containing a hetero ring...

546 15, 546 97, 424256, C07D49108, C07D491107, A61K 31445

Patent

active

042464137

ABSTRACT:
Substituted 6-oxamorphinans and 6-oxaisomorphinans have been found to possess potent analgetic, narcotic antagonist, antitussive and/or ADH inhibitory activity. The compounds are prepared by total synthesis and are not derived from opium alkaloids.

REFERENCES:
patent: 3853889 (1974-12-01), Monkovic et al.
patent: 3959290 (1976-05-01), Monkovic et al.
patent: 4016167 (1977-04-01), Montzka et al.
patent: 4154932 (1979-05-01), Montzka et al.

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