Organic compounds -- part of the class 532-570 series – Organic compounds – Carbohydrates or derivatives
Patent
1990-10-01
1994-04-12
Brown, Johnnie R.
Organic compounds -- part of the class 532-570 series
Organic compounds
Carbohydrates or derivatives
C07H 1708
Patent
active
053027051
ABSTRACT:
A 6-O-methylerythromycin A oxime derivative represented by the formula ##STR1## wherein X is a substituted benzyl group, a substituted phenyl group, an .alpha.-methylbenzyl group, an .alpha.-methylphenethyl group, a diphenylmethyl group, a trityl group, a dibenzosuberanyl group, or a group of the formula --(CH.sub.2).sub.n --R, and Y is a hydrogen atom, a substituted phenyl group or a 2-aminothiazol-4-ylmethylcarbonyl group, and a pharmaceutically acceptable salt thereof are disclosed. These compounds have antibacterial activity against erythromycin resistant bacteria.
REFERENCES:
patent: 4331803 (1982-05-01), Watanabe et al.
patent: 4349545 (1982-09-01), d'Ambrieres et al.
patent: 4680386 (1987-07-01), Morimoto et al.
patent: 4740502 (1988-04-01), Hannick et al.
patent: 4921839 (1990-05-01), Brain et al.
Asaka Toshifumi
Hatayama Katsuo
Kashimura Masato
Misawa Yoko
Morimoto Shigeo
Brown Johnnie R.
Pesele Elli
Taisho Pharmaceutical Co. Ltd.
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