6-(Nitrogen-containing heterocyclic)hydroxymethylpenicillanic ac

Drug – bio-affecting and body treating compositions – Antigen – epitope – or other immunospecific immunoeffector – Bacterium or component thereof or substance produced by said...

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260 2452R, 26032615, 424270, 424274, 424275, 424263, 546152, 546273, C07D49900

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active

043047793

ABSTRACT:
6-(Heterocyclic)hydroxymethylpenicillanic acids and compounds related thereto are prepared by reaction of a 6,6-dihalopenicillanic acid with a Grignard reagent and a heterocyclic aldehyde in an anhydrous aprotic solvent. The compounds possess useful antibacterial activity.

REFERENCES:
patent: 4207323 (1980-06-01), Beattie et al.

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