6-modified bicyclic nucleic acid analogs

Details 6-modified bicyclic nucleic acid analogs 6-modified bicyclic nucleic acid analogs

2008-05-29

2010-06-22

Lewis, Patrick T (Department: 1623)

Organic compounds -- part of the class 532-570 series

Organic compounds

Carbohydrates or derivatives

C536S023100, C514S043000

Reexamination Certificate

active

07741457

ABSTRACT:
The present invention provides 6-modified bicyclic nucleoside analogs and oligomeric compounds comprising these nucleoside analogs. In preferred embodiments the nucleoside analogs have either (R) or (S)-chirality at the 6-position. These bicyclicnucleoside analogs are useful for enhancing properties of oligomeric compounds including nuclease resistance.

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