6-keto-prostaglandin E.sub.1 derivatives

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...

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514530, 514570, 514571, 514573, 514613, 514621, 548533, 549415, 549473, 560 39, 560 40, 560118, 560121, 562444, 562445, 562500, 562503, 564169, 564189, C07C17700, A01K 31557

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047834803

ABSTRACT:
A 6-keto-prostaglandin E.sub.1 derivative of the formula: ##STR1## (wherein R.sup.1 represents an amino acid or amino alcohol residue, R.sup.2 represents a single bond or an alkylene group of from 1 to 4 carbon atoms, R.sup.3 represents (i) an alkyl group of from 1 to 8 carbon atoms, (ii) a cycloalkyl group of from 4 to 7 carbon atoms, which may be unsubstituted or substituted by at least one alkyl group of from 1 to 8 carbon atoms or (iii) a phenyl or phenoxy group, which may be unsubstituted or substituted by chlorine, trifluoromethyl or alkyl of from 1 to 3 carbon atoms, provided that when R.sup.2 represents a single bond R.sup.3 does not represent phenoxy)

REFERENCES:
Chemical Abstract, vol. 85, No. 11, Sep. 13th 1976, p. 512.
Chemical Abstract, vol. 84, No. 7, Feb. 16th 1976; p. 436.
Chemical Abstract, vol. 83, No. 15, Oct. 13th 1975, p. 471.

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