6-Hydroxyalkylamino-8-methyl-1,2,4-triazolo-[4,3-b]pyridazine an

Details 6-Hydroxyalkylamino-8-methyl-1,2,4-triazolo-[4,3-b]pyridazine an 6-Hydroxyalkylamino-8-methyl-1,2,4-triazolo-[4,3-b]pyridazine an

1983-11-22

1986-03-25

Berch, Mark L.

Organic compounds -- part of the class 532-570 series

Organic compounds

Four or more ring nitrogens in the bicyclo ring system

C07D48704, A61K 3141

Patent

active

045784647

ABSTRACT:
8-Methyl-1,2,4-triazolo[4,3-b]pyridazines having a hydroxyalkylamino substituent at the 6-position are described herein. The compounds involved are useful as bronchodilator agents and they are prepared by the reaction of 6-chloro-8-methyl-1,2,4-triazolo[4,3-b]-pyridazine with an appropriate amino alcohol.

REFERENCES:
patent: 3915968 (1975-10-01), Bellasio et al.
patent: 4136182 (1979-01-01), Lewis et al.
Kosary et al., Heterocycles, vol. 20 (5) 1983, pp. 749-752.

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