Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Heterocyclic carbon compounds containing a hetero ring...
Patent
1987-01-14
1988-12-27
Rizzo, Nicholas S.
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Heterocyclic carbon compounds containing a hetero ring...
514195, 540310, C07D49900, A61K 31415
Patent
active
047941090
ABSTRACT:
2-Heterocyclyl-lower alkyl-6-hydroxy-lower alkyl-2-penem compounds of the formula ##STR1## in which R.sub.1 represents lower alkyl substituted by hydroxy or protected hydroxy, R.sub.2 represents carboxy or functionally modified carboxy, R.sub.3 represents an unsaturated monocyclic azaheterocyclyl radical bonded via a tertiary ring nitrogen atom to the radical -A- and A represents a lower alkylene radical, optical isomers of compounds of the formula (I), mixtures of these optical isomers and salts of such compounds of the formula (I) that contain a salt-forming group have antibiotic properties. The novel compounds can be used, for example, in the form of antibiotically active preparations for the treatment of infectious diseases. The novel compounds can be manufactured in a manner known per se.
REFERENCES:
patent: 4272437 (1981-06-01), Menard
patent: 4301074 (1981-11-01), Christensen et al.
patent: 4347183 (1982-08-01), Afonso et al.
patent: 4395418 (1983-07-01), Ohki et al.
patent: 4482565 (1984-11-01), Foglio et al.
patent: 4540580 (1985-09-01), Afonso et al.
patent: 4617300 (1986-10-01), Girijavallabhan
patent: 4623643 (1986-11-01), Alpegiani et al.
Derwent Abstract of Japanese, 56/166194 (1981).
Derwent Abstract of Japanese, 58/105992 (1983).
The Journal of Antibiotics, vol. 40, No. 2, pp. 217-220 (2/87).
J. Org. Chem., vol. 43, No. 2, pp. 337-339 (1978).
Girijavallabhan et al., Tetrahedron Letters, vol. 22, No. 36, pp. 3485-3488 (1981).
Ciba-Geigy Corporation
Fishman Irving M.
Rizzo Nicholas S.
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