6-hydroxy-2(2-hydroxy-4-methoxyphenyl)benzofuran derivatives to

Details 6-hydroxy-2(2-hydroxy-4-methoxyphenyl)benzofuran derivatives to 6-hydroxy-2(2-hydroxy-4-methoxyphenyl)benzofuran derivatives to

1986-11-05

1987-12-22

Friedman, Stanley J.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Having -c-, wherein x is chalcogen, bonded directly to...

A61K 3136

Patent

active

047147113

ABSTRACT:
6-Hydroxy-2-(2-hydroxy-4-methoxyphenyl)benzofuran derivatives and related pharmaceutical compositions and methods of treatment are disclosed. The compounds are useful as inhibitors of mammalian leukotriene biosynthesis. As such, they are useful therapuetic agents for treating allergic conditions, asthma, cardiovascular disorders and inflammation.

REFERENCES:
J. L. Ingham et al., Phytochemistry, 1978, vol. 17, pp. 535-538.
P. M. Dewick et al., Phytochemistry, 1980, vol. 19, pp. 289-291.

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