Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...
Patent
1994-08-31
1997-01-14
Daus, Donald G.
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Having -c-, wherein x is chalcogen, bonded directly to...
548235, A61K 3142, C07D40304
Patent
active
055940196
ABSTRACT:
6-heterocyclic-4-amino-1,3,4,5-tetrahydrobenz[cd]indoles are provided which are useful in modifying the function of serotonin in mammals.
REFERENCES:
patent: 3336307 (1967-08-01), Shen
patent: 3671541 (1972-06-01), Bormann et al.
patent: 3674801 (1972-07-01), Bormann et al.
patent: 4057560 (1977-11-01), Bormann et al.
patent: 4110339 (1978-08-01), Bach et al.
patent: 4252803 (1981-02-01), Webb
patent: 4282240 (1981-08-01), Baldwin et al.
patent: 4447438 (1984-05-01), Ledelc et al.
patent: 4576959 (1986-03-01), Flaugh
patent: 4576969 (1983-03-01), Echigo et al.
patent: 4745126 (1988-05-01), Leander
patent: 4977172 (1990-12-01), Johnson et al.
patent: 4983622 (1991-01-01), Flaugh
patent: 5021438 (1991-06-01), Junge et al.
patent: 5039820 (1991-08-01), Kress et al.
patent: 5204340 (1993-04-01), Flaugh et al.
patent: 5212319 (1993-05-01), Kress et al.
patent: 5229410 (1993-07-01), Flaugh et al.
patent: 5266571 (1993-11-01), Amer
patent: 5397799 (1995-03-01), Kress et al.
Dorland's Illustrated Medical Dictionary, 26th Ed., Saunders, Philadelphia, 1981, p. 1193.
Flaugh, et al., J. Med. Chem., 1988, 31, 1746-1753.
Kruse, et al., J. Org. Chem., 49, 4761-4768 (1984).
Bach, et al., J. Med. Chem., 23, 481-491 (1980).
Derwent Abstract 57337 (1979).
Haefliger, et al., Tet. Lett., 25, No. 3, 289 (1984).
Chemical Abstracts 107, 39610b for JP62-63,567 (1987).
Glennon, J. Med. Chem., 30, 1 (1987).
T. W. Greene, Protective Group in Organic Synthesis, John Wiley and Sons (1981) Chapter 7 pp. 218-287.
J. W. Barton, Protective Group in Organic Synthesis, McOmie, ed., Plenum Press (1973) Chapter 2 pp. 43-61.
Schoenberg, et al., J. Org, Chem., 39, pp. 3327-3331 (1974).
Schoenberg, et al., J. Org. Chem., 39, p. 3318 (1974).
Raucher et al Tetrahedron Letters 21, 4061 (1980).
Nichols, et al., Org. Prep. & Proc. Int., 9, 277 (1977).
Leanna, et al., Tet. Lett., 30, 3935 (1989).
O. Mitsunobu, Synthesis, Jan. 1981, pp. 1-28.
J. P. Freemen, et al., Synthesis, Dec. 1974, pp. 894-895.
Sugi, et al., Bull. Chem. Soc. Jap., 43, p. 1489 (1970).
Morrison & Boyd, Chapter 22, Organic Chemistry, 3rd Ed. (1973) pp. 734-743.
Wong, et al., J. Neural Transm., 71 207-218 (1988).
Wong, et al., J. Neural Transm., 64, 251-269 (1985).
Heydrich, et al., J. Clin. Psych., 51(4) [Supp], 5 (1990).
Ray W. Fuller, Adv. in Drug. Res., 17, 349 (1988).
Saxena, et al., J. Card. Pharm., 15, [Supp 7], 517 (1990).
Burger, Ed, Medicinal Chemistry 2d Ed. Interscience, NY, 42 (1960).
Booher Richard N.
Flaugh Michael E.
Lawhorn David E.
Paget, Jr. Charles J.
Schaus John M.
Boone David E.
Daus Donald G.
Eli Lilly and Company
Jones Joseph A.
Taylor Douglas J.
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