6-heterocyclic-4-amino-1,2,2a,3,4,5-hexahydrobenz[cd]indoles

Organic compounds -- part of the class 532-570 series – Organic compounds – Heterocyclic carbon compounds containing a hetero ring...

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A61K 3142, C07D41304

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active

053470133

ABSTRACT:
6-Heterocyclic-4-amino-l,2,2a,3,4,5-hexahydrobenz[cd]indoles are provided which are useful in modifying the function of serotonin in mammals.

REFERENCES:
patent: 2809974 (1957-10-01), Kornfeld et al.
patent: 3336307 (1967-08-01), Shen
patent: 3671541 (1972-06-01), Bormann et al.
patent: 3674801 (1974-07-01), Bormann et al.
patent: 4057560 (1977-11-01), Bormann et al.
patent: 4110339 (1978-08-01), Bach et al.
patent: 4576959 (1986-03-01), Flaugh
patent: 4745126 (1988-05-01), Leander
patent: 4983622 (1991-01-01), Flaugh
patent: 5039820 (1991-08-01), Kress et al.
patent: 5229410 (1993-07-01), Flaugh et al.
Heydrich, et al., J. Clin. Psych., 51(4) [Supp], 5 (1990).
Ray W. Fuller, Adv. in Drug Res., 17, 349 (1988).
Saxena, et al., J. Card. Pharm., 15 [Supp 7], 517 (1990).
Flaugh et al., J. Med. Chem., 1988, 31, 1746-1753.
Kornfeld, et al., J.A.C.S., 78, 3087 (1956).
Kruse, et al., J. Org. Chem., 49 4761-4768 (1984).
Bach, et al., J. Med. Chem., 23, 481-491 (1980).
Glennon, J. Med. Chem., 30, 1 (1987).
T. W. Greene, Protective Group in Organic Synthesis, John Wiley and Sons (1981) Chapter 7.
J. W. Barton, Protective Group in Organic Synthesis, McOmie, ed., Plenum Press (1973) Chapter 2.
The Vocabulary of Organic Chemistry, Orchin, et al., John Wiley and Sons, Inc., publishers, p. 126.
Schoenberg, et al., J. Org. Chem., 39, p. 3327 (1974).
Schoenberg, et al., J. Org. Chem., 39, p. 3318 (1974).
Tetrahedron Letters 21, 4061 (1980).
Nichols, et al., Org. Prep. & Proc. Int., 9, 277 (1977).
Leanna, et al., Tet. Lett., 30, 3935 (1989).
O. Mitsunobu, Synthesis, Jan. 1981, p. 1.
J. P. Freeman, et al., Synthesis, Dec. 1974, p. 894.
Sugi, et al., Bull. Chem. Soc. Jap., 43, p. 1489 (1970).
Morrison & Boyd, Chapter 22, Organic Chemistry, 3rd Ed. (1973).
Wong, et al., J. Neural Transm., 71, 207-218 (1988).
Wong, et al., J. Neural Transm., 64, 251-269 (1985).

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