6-Halo-7,8-d ihydroxy-1-(hydroxyphenyl)-2,3,4,5-tetrahydro-1H-3-

Drug – bio-affecting and body treating compositions – Antigen – epitope – or other immunospecific immunoeffector – Bacterium or component thereof or substance produced by said...

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260239BB, A61K 3155, C07D22316

Patent

active

041972970

ABSTRACT:
6-Halo-7,8-dihydroxy-1-phenyl-2,3,4,5-tetrahydro-1H-3-benzazepines whose structures have a hydroxy group substituted on the 1-phenyl ring have potent and specific antihypertensive activity by means of their peripheral dopaminergic effect. The lead compound of the series is 6-chloro-7,8-dihydroxy-(p-hydroxyphenyl)-2,3,4,5-tetrahydro-1H-3-benzazepi ne methane sulfonate.

REFERENCES:
patent: 3496166 (1970-02-01), Mull et al.

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