6-Halo-1,2,3,4-tetrahydr oquinazoline-4-spiro-4-imidazolidine-2,

Details 6-Halo-1,2,3,4-tetrahydr oquinazoline-4-spiro-4-imidazolidine-2, 6-Halo-1,2,3,4-tetrahydr oquinazoline-4-spiro-4-imidazolidine-2,

1987-10-29

1989-08-08

Sutto, Anton H.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Having -c-, wherein x is chalcogen, bonded directly to...

544231, 548485, 560 30, A61K 31505, C07D48710

Patent

active

048552984

ABSTRACT:
A quinazolinone derivative of the formula: ##STR1## wherein R.sup.1 is hydrogen atom or a halogen atom, or a salt thereof and processes for preparing the same are disclosed. The quinazolinone derivative (I) is useful for treatment of diabetic complications.

REFERENCES:
patent: 4248882 (1981-02-01), Sarges
patent: 4273775 (1981-06-01), Sarges
patent: 4282229 (1981-08-01), Sarsas
patent: 4533667 (1985-08-01), Hutchison
patent: 4575507 (1986-03-01), Lipinski
patent: 4762839 (1988-08-01), Yamada et al.
Capuano et al., I, Chem. Ber., 103, p. 2394 (1970).
Capuano et al., II, Chem. Ber., 110, p. 3849 (1977).

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