6-ethyl mitomycin derivatives

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...

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548422, C07D48722, A61K 3140

Patent

active

053346114

ABSTRACT:
Novel mitomycin derivatives represented by the formula (I) are obtained by introducing a substituent at the 6-position. The mitomycin derivatives of the present invention have an antitumor activity.

REFERENCES:
patent: 4374774 (1983-02-01), Kasai et al.
patent: 4880825 (1989-11-01), Kasai et al.
patent: 5068349 (1991-11-01), Kanda et al.
Chemical Abstracts, vol. 83, No. 21, Nov. 24, 1975, Columbus, Ohio, US; Abstract No. 179026b, Y. Fujimoto et al., "Mitomycin derivatives".
Abstract No. 179026b--Chemical abstracts, vol. 83, No. 21, Nov. 24, 1975, Columbus, Ohio, US; Y. Fujimoto et al., "Mitomycin derivatives" * abstract*.

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