6'-Epi-fortimicin A and B derivatives

Organic compounds -- part of the class 532-570 series – Organic compounds – Carbohydrates or derivatives

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424180, 536 18, A61K 3171, C07H 1522

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active

042140757

ABSTRACT:
6'-Epi-fortimicin A and B derivatives represented by the formula ##STR1## wherein R.sub.1 is hydrogen or loweralkyl, R.sub.2 is hydrogen or loweralkyl and R.sub.3 is selected from the group consisting of hydrogen, loweralkyl, aminoloweralkyl, N-loweralkylaminoloweralkyl, N,N-diloweralkylaminoloweralkyl, aminohydroxyloweralkyl, N-loweralkylaminohydroxyloweralkyl, hydroxyloweralkyl, acyl, aminoacyl, hydroxyacyl, N-monoloweralkylaminoacyl, N,N-diloweralkylaminoacyl, hydroxy-substituted aminoacyl or an amino acid residue; the pharmaceutically acceptable salts thereof; intermediates useful in their preparation, compositions employing the compounds; and methods of using the compounds. The compounds are useful as antibiotics.

REFERENCES:
patent: 3929762 (1975-12-01), Umezawa et al.
patent: 3931400 (1976-01-01), Nara et al.
patent: 3976768 (1976-08-01), Nara et al.
patent: 4078138 (1978-03-01), Akita et al.
patent: 4085208 (1978-04-01), Mallams et al.
patent: 4091032 (1978-05-01), Tadanier et al.

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