6-Chloro- or 6-bromo-1,2-dihydro-3H-pyrrolo[1,2-a]-pyrrole-1-car

Details 6-Chloro- or 6-bromo-1,2-dihydro-3H-pyrrolo[1,2-a]-pyrrole-1-car 6-Chloro- or 6-bromo-1,2-dihydro-3H-pyrrolo[1,2-a]-pyrrole-1-car

1980-06-09

1982-08-17

Rollins, Alton D.

Drug, bio-affecting and body treating compositions

Antigen, epitope, or other immunospecific immunoeffector

Bacterium or component thereof or substance produced by said...

2603262, 26032622, 26032625, 26032631, 26032643, 424253, 424267, 424274, 544275, 546200, A61K 3140, A61K 3152, C07D48704, C07F 108

Patent

active

043449433

ABSTRACT:
Novel 5-aroyl-6-chloro- or 6-bromo-1,2-dihydro-3H-pyrrolo[1,2-a]pyrrole-7-carboxylic acids represented by the formula ##STR1## and the pharmaceutically acceptable, non-toxic esters and salts thereof, wherein Y is chloro or bromo and Ar is an optionally substituted phenyl, 2-furyl, or 2-thienyl ring or a 3-furyl, 3-thienyl, 2-pyrrolyl or 1-alkyl-2-pyrrolyl ring. These compounds are useful as anti-inflammatory, analgesic and antipyretic agents and as smooth muscle relaxants.

REFERENCES:
patent: 4087539 (1978-05-01), Muchowski et al.
patent: 4089969 (1978-05-01), Muchowski et al.
patent: 4097579 (1978-06-01), Muchowski et al.
patent: 4140698 (1979-02-01), Van Horn et al.
patent: 4232038 (1980-11-01), Kluge et al.

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