6-chloro-3,4-dihydro-pyrano [2,3-b]pyridines having the R config

Organic compounds -- part of the class 532-570 series – Organic compounds – Heterocyclic carbon compounds containing a hetero ring...

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546 14, 546303, 546339, 546344, 546345, C07F 702, C07D491048, C07D21361

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active

050683330

ABSTRACT:
The present invention relates to processes and intermediates for the preparation of spiro-heteroazolones. The latter compounds are useful as aldose reductase inhibitors.

REFERENCES:
Chemical Abstracts, vol. 111(15), Abst. No. 134,148-y, Oct. 09, 1989.
Abstracting Eur. Pat. Appl. EP-306,251, Mar. 08, 1989.
L. G. Wade, Jr., Organic Chemistry, p. 349, Prentice-Hall, Inc., publishers 1987.
March, Advanced Organic Chemistry, Second Edition, pp. 108-111, McGraw Hill Pub. 1977.
Schultz et al., J. Org. Chem., 51, 838-41 (1986).
Bargar et al., J. Heterocyclic Chem., 22, 1583 (1985).
Mallet et al., Tetrahedron, 35, 1625-31 (1979).
Bargar et al., J. Med. Chem., 29, 1590-1595 (1985).

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