6' Carbamate esters of zearalanol and its derivatives

Details 6' Carbamate esters of zearalanol and its derivatives 6' Carbamate esters of zearalanol and its derivatives

1988-01-19

1990-02-20

Waddell, Frederick E.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Having -c-, wherein x is chalcogen, bonded directly to...

5142282, 5142335, 514320, A61K 31335

Patent

active

049027115

ABSTRACT:
6' Carbamate esters of zearalanol and its derivatives are used to promote growth in ruminants. The compounds have the structural formula: ##STR1## wherein R.sub.1 and R.sub.2, which may be the same or different, are H, X, or COX, where X is an alkyl group having from 1-6 carbon atoms; and R is NH-Y, where Y is an alkyl group having from 1-6 carbon atoms or a five-membered or six-membered ring; N(C.sub.n H.sub.2n+1).sub.2, where n is an integer from 1 to 6; or a five-membered or six-membered heterocyclic ring having one N heteroatom and up to one other heteroatom selected from the group consisting of N, S, and O heteroatoms.

REFERENCES:
patent: 3196019 (1965-07-01), Andrews et al.
patent: 3239341 (1966-03-01), Hodge et al.
patent: 3239345 (1966-03-01), Hodge et al.
patent: 3239346 (1966-03-01), Hodge et al.
patent: 3239348 (1966-03-01), Hodge et al.
patent: 3239354 (1966-03-01), Hodge et al.
patent: 3860616 (1975-01-01), Hoffsommer et al.
patent: 4088658 (1978-05-01), Robertson
patent: 4409392 (1983-10-01), Hodge
patent: 4443470 (1984-04-01), Hodge et al.
Hidy et al, "Zearalenone and Some Derivatives: Productio nand Biological Activities", Adv. Appl. Microbiol., 22:59-82 (1977).
Shipchandler, "Chemistry of Zearalanone and Some of Its Derivatives", Heterocycles, 3(6):471-520 (1975).
Peters et al., "A Stereoselective Synthetic Route to (R)-Zearalanone", J. Med. Chem., vol. 19, No. 4, 215-217 (1975).

Affiliated with

Also associated with

Rating

6' Carbamate esters of zearalanol and its derivatives does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with 6' Carbamate esters of zearalanol and its derivatives, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and 6' Carbamate esters of zearalanol and its derivatives will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFUS-PAI-O-1616460