6-carbamade erythromycin derivatives

Details 6-carbamade erythromycin derivatives 6-carbamade erythromycin derivatives

1986-08-26

1989-05-02

Brown, Johnnie R.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Carbohydrate doai

536 72, 536 74, A61K 3170, C07H 1708

Patent

active

048268208

ABSTRACT:
Antibacterially active 6-carbamate erythromycin derivatives of formula I and their pharmaceutically acceptable esters and acid addition salts; ##STR1## wherein: R.sup.1 or R.sup.2 is optionally substituted amino, or R.sup.1 or R.sup.2 +R.sup.5 is --O--C(R.sup.A)(R.sup.B)--O--, and R.sup.2 or R.sup.1 is H, or R.sup.1 +R.sup.2 is oxo, oxime, substituted oxime, or imino;

REFERENCES:
patent: 4133950 (1979-01-01), Myers
Morrison et al., Organic Chemistry, 3rd ed., Allyn and Bacon, Inc., 1973, p. 1044.
The Merck Index, 10th Edition, 1983, pp. 531-532, Ref. No. 3624, "Erythromycin"; Merck & Co., Inc., Rahway, N.J., U.S.

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