Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...
Patent
1994-01-31
1995-11-21
Dentz, Bernard
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Having -c-, wherein x is chalcogen, bonded directly to...
514 81, 546 23, 546113, A61K 31435, C07D47104
Patent
active
054687578
ABSTRACT:
Selected acid functional 6-azaindole type derivatives effective as thromboxane synthase inhibitors having the formula (II): ##STR1## where n is an integer from zero to 3, m is an integer from zero to 2, R.sub.1 and R.sub.2 are monovalent radicals, --(L.sub.a)-- is a linking group of 4 to 8 chain atoms, and A is an acidic group.
REFERENCES:
patent: 4766129 (1988-08-01), Schnorrenberg et al.
Mahadevan et al., Tet. Letters vol. 49 (33), pp. 7337-7352 (Aug. 1993).
Dvorakova et al., Collection of Czech. Chem. Communications, pp. 1419-1428 (1993).
Jakubowski Joseph A.
Palkowitz Alan D.
Sigmund Sandra K.
Benjamin Roger S.
Boone David E.
Dahling Gerald V.
Dentz Bernard
Eli Lilly and Company
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