6-Aminocarbonyl purine 3',5'-cyclic nucleotides

Details 6-Aminocarbonyl purine 3',5'-cyclic nucleotides 6-Aminocarbonyl purine 3',5'-cyclic nucleotides

1973-09-17

1977-07-26

Brown, Johnnie R.

Organic compounds -- part of the class 532-570 series

Organic compounds

Carbohydrates or derivatives

424180, 536 28, C07H 1920

Patent

active

040384802

ABSTRACT:
N.sup.6 -Carbamoyl and -carbonyl analogs of adenosine 3',5'-cyclic phosphate (cAMP) are prepared and variously demonstrated to exhibit kinase, adrenal steroidogenisis and lipolysis activation superior to cAMP, inhibit phosphodiesterase, and found to increase cardiac output or, in particular cases, to lower blood pressure.

REFERENCES:
patent: 3380996 (1968-04-01), Honjo et al.
patent: 3535207 (1970-10-01), Shiro et al.
patent: 3712885 (1973-01-01), Weimann et al.

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