6-amino-1,4-hexahydro-1H-diazepine derivatives

Details 6-amino-1,4-hexahydro-1H-diazepine derivatives 6-amino-1,4-hexahydro-1H-diazepine derivatives

1991-03-11

1992-11-24

Tsang, Cecilia

Organic compounds -- part of the class 532-570 series

Organic compounds

Unsubstituted hydrocarbyl chain between the ring and the -c-...

540472, 540556, C07D24308, C07D48708

Patent

active

051663414

ABSTRACT:
Indazole-3-carboxylic acid derivatives represented by the following general formula (I) and their physiologically acceptable acid addition salts or quaternary ammonium salts, ##STR1## are useful as a potent and selective antagonist of serotonin 3 (5-HT.sub.3) receptor. Also disclosed are compounds of the formula ##STR2## which are useful as intermediates in the production of the disclosed final product compounds.

REFERENCES:
patent: 4207327 (1980-06-01), Lunsford et al.
patent: 4474964 (1984-10-01), Ibuki et al.
Gaertner, Journal of Heterocyclic Chemistry, vol. 18, No. 3, Jun., 1971, pp. 519-521.
Ungnade et al., Journal of Organic Chemistry, vol. 30, No. 2 (1965), pp. 354-359.
Bagga et al., Journal of The Chemical Society, Chemical Communications, (1987), pp. 259-261.
Beilsteins Handbuch der Organischen Chemie, 4th Edition 3rd and 4th Supplementary Series, vol. 25/3 (1981) p. 1982.
Saari et al., J. Org. Chem., vol. 36, No. 12, (1971), pp. 1711-1714.
Kon et al., Chemical Abstract vol. 112, No. 7473w (1989).

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