6-Amidocyclonocardicins

Drug – bio-affecting and body treating compositions – Antigen – epitope – or other immunospecific immunoeffector – Fungus – except allergen – or component thereof or substance...

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2602452R, A61K 3140, C07D48714

Patent

active

043748490

ABSTRACT:
Disclosed are 6-amidocyclonocardicins (I) and their pharmaceutically acceptable salts and esters which are useful as antibiotics ##STR1## wherein: R is NH.sub.2, R.sup.1 NH, R.sup.1 is acyl. Also disclosed are processes for the preparation of such compounds; pharmaceutical compositions comprising such compounds; and methods of treatment comprising administering such compounds and compositions when an antibiotic effect is indicated.

REFERENCES:
Aoki et al., The Journal of Antibiotics, May 1976, pp. 492-500.

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