6.alpha.-Methoxy-4.alpha.-hydroxy-2.beta.-hydroxymethyl-3.a lpha

Details 6.alpha.-Methoxy-4.alpha.-hydroxy-2.beta.-hydroxymethyl-3.a lpha 6.alpha.-Methoxy-4.alpha.-hydroxy-2.beta.-hydroxymethyl-3.a lpha

1976-04-14

1977-09-13

Jaisle, Cecilia M. S.

Chemistry of carbon compounds

Miscellaneous organic carbon compounds

C-metal

260343, 2603433R, 2603435, 2603457P, 2603458P, 2603473, 2603474, 2604055, 424283, 542427, 542426, C07D49304

Patent

active

040481948

ABSTRACT:
The present specification provides novel intermediates and novel processes for the synthesis of Thromboxane B.sub.2 (11a-homo-11a-oxa-PGF.sub.2.alpha.), its 15-epimer, and various carboxyl derivatives thereof. In particular, there are disclosed various bicyclic tetrahydropyran containing lactones useful in the above processes, and corresponding acyclic lactones.

REFERENCES:
patent: 3971826 (1976-07-01), Hess et al.

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