Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...
Patent
1990-04-03
1993-01-05
Ivy, C. Warren
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Having -c-, wherein x is chalcogen, bonded directly to...
514824, 514548, 549292, 560119, A61K 31365, C07D30930, C07C 6974
Patent
active
051771047
ABSTRACT:
Compounds of the formula ##STR1## and pharmaceutically acceptable salts thereof have been found to possess activity as cell-selective HMG-CoA reductase inhibitors, thus making them useful as antihypercholesterolemic agents. In the above formula, ##STR2## R.sup.1 is hydrogen, alkyl, cycloalkyl, aryl or arylalkyl; and R.sup.2 is hydrogen, alkyl, ammonium, or alkali metal.
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Chao Sam T.
Gordon Eric M.
Varma Ravi K.
E. R. Squibb & Sons Inc.
Gaul Timothy J.
Ivy C. Warren
Owens Amelia A.
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