6-Alkylamino-2-methyl-2′-(N-methyl substituted...

Organic compounds -- part of the class 532-570 series – Organic compounds – Heterocyclic carbon compounds containing a hetero ring...

Reexamination Certificate

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Details

C549S060000, C549S365000, C546S282700, C546S283100, C514S457000, C514S456000, C514S444000, C514S337000

Reexamination Certificate

active

11491320

ABSTRACT:
The present invention relates to a noble 6-alkylamino-2-methyl-2′-(N-methyl substituted sulfonamido)methyl-2H-1-benzopyran derivative, a method for preparing the same with high efficiency using a parallel synthetic method, one of combinatorial chemical synthetic techniques, and a use of the novel compound showing a high inhibitory effect to 5-lipoxygenase (5-LO) activity for preventing and treating leukotriene (LTA4, B4, C4, D4) activation-related diseases such as inflammatory diseases, rheumatoid arthritis, colitis, asthma and psoriasis.

REFERENCES:
patent: 5646308 (1997-07-01), Koga et al.
patent: 5696137 (1997-12-01), Heine et al.
patent: 6395909 (2002-05-01), Bell et al.

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